Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jankowski, Nicholas | - |
dc.contributor.author | Dietrich, Julian | - |
dc.contributor.author | Krause, Norbert | - |
dc.date.accessioned | 2024-01-22T14:56:58Z | - |
dc.date.available | 2024-01-22T14:56:58Z | - |
dc.date.issued | 2022-08-08 | - |
dc.identifier.uri | http://hdl.handle.net/2003/42292 | - |
dc.identifier.uri | http://dx.doi.org/10.17877/DE290R-24128 | - |
dc.description.abstract | A transition metal-free method for the cycloisomerization of propargylic amides to oxazoles was developed. The reaction utilizes in situ generated hydrogen chloride in hexafluoroisopropanol (HFIP). With the aid of Design of Experiments optimization a wide range of substrates was transformed into the desired oxazoles. The method allows product formation without side reactions eliminating the need for extensive work-up and purification. | en |
dc.language.iso | en | de |
dc.relation.ispartofseries | Advanced synthesis & catalysis;364(19) | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | de |
dc.subject | Brønsted acid catalysis | en |
dc.subject | Cycloisomerization | en |
dc.subject | Design of Experiments | en |
dc.subject | Solvent effects | en |
dc.subject | Transition metal-free synthesis | en |
dc.subject.ddc | 540 | - |
dc.title | Transition metal-free cycloisomerization of propargylic amides to oxazoles in hexafluoroisopropanol (HFIP) | en |
dc.type | Text | de |
dc.type.publicationtype | ResearchArticle | de |
dcterms.accessRights | open access | - |
eldorado.secondarypublication | true | de |
eldorado.secondarypublication.primaryidentifier | https://doi.org/10.1002/adsc.202200559 | de |
eldorado.secondarypublication.primarycitation | N. Jankowski, J. Dietrich, N. Krause, Adv. Synth. Catal. 2022, 364, 3404. | de |
Appears in Collections: | Organische Chemie |
Files in This Item:
File | Description | Size | Format | |
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Adv Synth Catal - 2022 - Jankowski - Transition Metal‐Free Cycloisomerization of Propargylic Amides to Oxazoles in.pdf | DNB | 4.08 MB | Adobe PDF | View/Open |
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